ZNF3

Protein-coding gene in the species Homo sapiens
ZNF3
Identifiers
AliasesZNF3, A8-51, HF.12, KOX25, PP838, Zfp113, zinc finger protein 3
External IDsOMIM: 194510 MGI: 1929116 HomoloGene: 50027 GeneCards: ZNF3
Gene location (Human)
Chromosome 7 (human)
Chr.Chromosome 7 (human)[1]
Chromosome 7 (human)
Genomic location for ZNF3
Genomic location for ZNF3
Band7q22.1Start100,064,033 bp[1]
End100,082,548 bp[1]
Gene location (Mouse)
Chromosome 5 (mouse)
Chr.Chromosome 5 (mouse)[2]
Chromosome 5 (mouse)
Genomic location for ZNF3
Genomic location for ZNF3
Band5|5 G2Start138,137,964 bp[2]
End138,154,006 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • right uterine tube

  • ganglionic eminence

  • secondary oocyte

  • sural nerve

  • rectum

  • transverse colon

  • Achilles tendon

  • right lobe of liver

  • bronchial epithelial cell

  • body of pancreas
Top expressed in
  • neural tube

  • ganglionic eminence

  • female urethra

  • secondary oocyte

  • proximal tubule

  • medial ganglionic eminence

  • otic placode

  • saccule

  • Paneth cell

  • primitive streak
More reference expression data
BioGPS




More reference expression data
Gene ontology
Molecular function
  • DNA-binding transcription factor activity
  • DNA binding
  • zinc ion binding
  • protein binding
  • metal ion binding
  • identical protein binding
  • nucleic acid binding
  • DNA-binding transcription factor activity, RNA polymerase II-specific
Cellular component
  • intracellular anatomical structure
  • nucleus
Biological process
  • multicellular organism development
  • leukocyte activation
  • cell differentiation
  • regulation of transcription, DNA-templated
  • transcription, DNA-templated
  • regulation of transcription by RNA polymerase II
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

7551

56314

Ensembl

ENSG00000166526

ENSMUSG00000037007

UniProt

P17036
Q86U76

n/a

RefSeq (mRNA)
NM_001278284
NM_001278287
NM_001278290
NM_001278291
NM_001278292

NM_017715
NM_032924
NM_001318135
NM_001318136
NM_001318137

NM_019747

RefSeq (protein)
NP_001265213
NP_001265216
NP_001265219
NP_001265220
NP_001265221

NP_001305064
NP_001305065
NP_001305066
NP_060185
NP_116313
NP_001349704
NP_001349705
NP_001349706
NP_001358139
NP_001358140
NP_001358141
NP_001358142
NP_001358143
NP_001358144
NP_001358145
NP_001358146
NP_001358147
NP_001265220.1
NP_001265221.1

n/a

Location (UCSC)Chr 7: 100.06 – 100.08 MbChr 5: 138.14 – 138.15 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Zinc finger protein 3 is a protein that in humans is encoded by the ZNF3 gene.

See also

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000166526 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000037007 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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(1) Basic domains
(1.1) Basic leucine zipper (bZIP)
(1.2) Basic helix-loop-helix (bHLH)
Group A
Group B
Group C
bHLH-PAS
Group D
Group E
Group F
bHLH-COE
(1.3) bHLH-ZIP
(1.4) NF-1
(1.5) RF-X
(1.6) Basic helix-span-helix (bHSH)
(2) Zinc finger DNA-binding domains
(2.1) Nuclear receptor (Cys4)
subfamily 1
subfamily 2
subfamily 3
subfamily 4
subfamily 5
subfamily 6
subfamily 0
(2.2) Other Cys4
(2.3) Cys2His2
(2.4) Cys6
(2.5) Alternating composition
(2.6) WRKY
(3) Helix-turn-helix domains
(3.1) Homeodomain
Antennapedia
ANTP class
protoHOX
Hox-like
metaHOX
NK-like
other
(3.2) Paired box
(3.3) Fork head / winged helix
(3.4) Heat shock factors
(3.5) Tryptophan clusters
(3.6) TEA domain
  • transcriptional enhancer factor
(4) β-Scaffold factors with minor groove contacts
(4.1) Rel homology region
(4.2) STAT
(4.3) p53-like
(4.4) MADS box
(4.6) TATA-binding proteins
(4.7) High-mobility group
(4.9) Grainyhead
(4.10) Cold-shock domain
(4.11) Runt
(0) Other transcription factors
(0.2) HMGI(Y)
(0.3) Pocket domain
(0.5) AP-2/EREBP-related factors
(0.6) Miscellaneous
see also transcription factor/coregulator deficiencies