4,5-Dihidroorotična kiselina

4,5-Dihidroorotična kiselina
IUPAC ime
 
2,6-diokso-1,3-diazinan-4-karboksilna kiselina
Identifikacija
CAS registarski broj 155-54-4
PubChem[1][2] 648
ChemSpider[3] 628 DaY
MeSH 4,5-dihydroorotic+acid
ChEBI 30865
ChEMBL[4] CHEMBL75782 DaY
Jmol-3D slike Slika 1
SMILES

O=C1NC(=O)NC(C(=O)O)C1

InChI

InChI=1S/C5H6N2O4/c8-3-1-2(4(9)10)6-5(11)7-3/h2H,1H2,(H,9,10)(H2,6,7,8,11) DaY
Kod: UFIVEPVSAGBUSI-UHFFFAOYSA-N DaY

InChI=1/C5H6N2O4/c8-3-1-2(4(9)10)6-5(11)7-3/h2H,1H2,(H,9,10)(H2,6,7,8,11)
Kod: UFIVEPVSAGBUSI-UHFFFAOYAI

Svojstva
Molekulska formula C5H6N2O4
Molarna masa 158,112 g/mol

 DaY (šta je ovo?)   (verifikuj)

Ukoliko nije drugačije napomenuto, podaci se odnose na standardno stanje (25 °C, 100 kPa) materijala

Infobox references

4,5-Dihidroorotična kiselina je derivat orotične kiseline koji služi kao intermedijer u biosintezi pirimidina.[5]

Reference

  1. ↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519.  edit
  2. ↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1. 
  3. ↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846.  edit
  4. ↑ Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”. Nucleic Acids Res 40 (Database issue): D1100-7. DOI:10.1093/nar/gkr777. PMID 21948594.  edit
  5. ↑ Francois Lacroute (March 1968). „Regulation of Pyrimidine Biosynthesis in Saccharomyces cerevisiae1”. J. Bacteriol. 95: 824-832. Arhivirano iz originala na datum 2020-09-18. Pristupljeno 2014-04-11. 
  • p
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Metabolizam purina
R5P→IMP: R5P • PRPP • PRA • GAR • FGAR • FGAM • AIR • CAIR • SAICAR • AICAR • FAICAR

IMP→AMP: Adenilosukcinat

IMP→GMP: Ksantozin monofosfat
Metabolizam pirimidina

M: MET

mt, k, c/g/r/p/y/i, f/h/s/l/o/e, a/u, n, m

k, cgrp/y/i, f/h/s/l/o/e, au, n, m, epon

m (A16/C10), i (k, c/g/r/p/y/i, f/h/s/o/e, a/u, n, m)