Flavokavain B
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| Names | |
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| Preferred IUPAC name 2′-Hydroxy-4′,6′-dimethoxychalcone | |
| Other names Flavokawain B | |
| Identifiers | |
CAS Number |
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3D model (JSmol) |
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Beilstein Reference | 2059845 |
PubChem CID |
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| UNII |
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CompTox Dashboard (EPA) |
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| Properties | |
Chemical formula | C17H16O4 |
| Molar mass | 284.311 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).  Y verify (what is  Y N ?) Infobox references | |
Chemical compound
Flavokavain B is a flavokavain found in the kava plant.[1] In 2010 a paper was published identifying it as a glutathione-depleting hepatotoxin.[2]
FKB is said by enthusiasts to occur at higher concentrations in "tudei" kava strains, which are generally considered less desirable.
See also
- Kavalactone
References
- ^ Dharmaratne, H. Ranjith W.; N. P. Dhammika Nanayakkara; Ikhlas A. Khan (February 2002). "Kavalactones from Piper methysticum, and their 13C NMR spectroscopic analyses". Phytochemistry. 59 (4): 429–33. doi:10.1016/S0031-9422(01)00443-5. PMID 11830162.
- ^ Zhou P., Gross S., Liu J.-H., Yu B.-Y., Feng L.-L., Nolta J., Sharma V., Piwnica-Worms D., Qiu S.X 'Flavokawain B, the hepatotoxic constituent from kava root, induces GSH-sensitive oxidative stress through modulation of IKK/NF-κB and MAPK signaling pathways . FASEB Journal 2010 24:12 (4722-4732)
External links
- Flavokawain B at the United States National Library of Medicine
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Kava
- Kava
- Kava culture
- Coconut shell cup
| Kavalactones | |
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| Flavokavains |
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| Other |
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