2F-NENDCK

Chemical compound
2F-NENDCK
Identifiers
  • 2-(ethylamino)-2-(2-fluorophenyl)cyclohexan-1-one
CAS Number
  • 2850352-64-4 checkY
PubChem CID
  • 168323042
Chemical and physical data
FormulaC14H18FNO
Molar mass235.302 g·mol−1
3D model (JSmol)
  • Interactive image
  • CCNC1(CCCCC1=O)C2=CC=CC=C2F
InChI
  • InChI=1S/C14H18FNO/c1-2-16-14(10-6-5-9-13(14)17)11-7-3-4-8-12(11)15/h3-4,7-8,16H,2,5-6,9-10H2,1H3
  • Key:RTXKYSLDFKUESF-UHFFFAOYSA-N

2F-NENDCK (2-Fluoro-N-Ethylnordeschloroketamine, 2'-Fluoro-2-Oxo-Phenylcyclohexylethylamine, 2'-Fluoro-2-Oxo-PCE) is a recreational designer drug from the arylcyclohexylamine family, with dissociative effects. It was first identified in Australia in 2022,[1] and has subsequently been found in China and Taiwan.[2][3]

See also

  • 2-Fluorodeschloroketamine
  • 3-Fluorodeschloroketamine
  • Fluorexetamine
  • Methoxetamine
  • N-Ethylnorketamine

References

  1. ^ Burke M (3 November 2022). "Alarm sounded after chemists discover new analogue of ketamine in Australia". Chemistry World.
  2. ^ Yen YT, Tsai YS, Su WL, Huang DY, Wu HH, Tseng SH, et al. (December 2022). "New ketamine analogue: 2-fluorodeschloro-N-ethyl-ketamine and its suggested metabolites". Forensic Science International. 341: 111501. doi:10.1016/j.forsciint.2022.111501. PMID 36274344. S2CID 252975335.
  3. ^ Wang KD, Yuan XL, Liu C, Cao FQ, Zhang YR, Liu WB, He SY (January 2023). "Identification of three novel new psychoactive substances 4F-AB-BUTINACA, AB-PHETINACA, and 2F-NENDCK". Drug Testing and Analysis. 15 (1): 115–122. doi:10.1002/dta.3359. PMID 35986510. S2CID 251693947.
Glutamate receptor modulators
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Ionotropic glutamate receptor modulators
AMPARTooltip α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor
KARTooltip Kainate receptor
NMDARTooltip N-Methyl-D-aspartate receptor
  • See also: Receptor/signaling modulators
  • Metabotropic glutamate receptor modulators
  • Glutamate metabolism/transport modulators
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Group I
mGluR1Tooltip Metabotropic glutamate receptor 1
mGluR5Tooltip Metabotropic glutamate receptor 5
Group II
mGluR2Tooltip Metabotropic glutamate receptor 2
mGluR3Tooltip Metabotropic glutamate receptor 3
Group III
mGluR4Tooltip Metabotropic glutamate receptor 4
  • Antagonists: CPPG
  • MAP4
  • MPPG
  • MSOP
  • MTPG
  • UBP-1112
mGluR6Tooltip Metabotropic glutamate receptor 6
  • Antagonists: CPPG
  • MAP4
  • MPPG
  • MSOP
  • MTPG
  • UBP-1112
mGluR7Tooltip Metabotropic glutamate receptor 7
  • Antagonists: CPPG
  • MAP4
  • MMPIP
  • MPPG
  • MSOP
  • MTPG
  • UBP-1112
  • XAP044; Negative allosteric modulators: ADX71743
mGluR8Tooltip Metabotropic glutamate receptor 8
  • Antagonists: CPPG
  • MAP4
  • MPPG
  • MSOP
  • MTPG
  • UBP-1112
See also: Receptor/signaling modulators • Ionotropic glutamate receptor modulators • Glutamate metabolism/transport modulators


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