Sarkozin dehidrogenaza
| Sarkozin dehidrogenaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.5.8.3 | ||||||||
| CAS broj | 93389-49-2&title= 37228-65-2, 93389-49-2 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Sarkozin dehidrogenaza (EC 1.5.8.3, sarkozinska N-demetilaza, monometilglicinska dehidrogenaza, sarkozin:(akceptor) oksidoreduktaza (demetilacija)) je enzim sa sistematskim imenom sarkozin:elektron-transfer flavoprotein oksidoreduktaza (demetilacija).[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- sarkozin + H2O + elektron-transfer flavoprotein glicin + formaldehid + redukovani elektron-transfer flavoprotein
Ovaj enzim je flavoprotein (FMN). Tetrahidrofolat je takođe supstrat, pri čemu se konvertuje u N5,N10-metilintetrahidrofolat.
Reference
- ^ Hoskins, D.D. & MacKenzie, C.G. (1961). „Solubilization and electron transfer flavoprotein requirement of mitochondrial sarcosine dehydrogenase and dimethylglycine dehydrogenase”. J. Biol. Chem. 236: 177—183. PMID 13716069.
- ^ Frisell, W.R. & MacKenzie, C.G. (1962). „Separation and purification of sarcosine dehydrogenase and dimethylglycine dehydrogenase”. J. Biol. Chem. 237: 94—98. PMID 13895406.
- ^ Steenkamp, D.J. & Husain, M. (1982). „The effect of tetrahydrofolate on the reduction of electron transfer flavoprotein by sarcosine and dimethylglycine dehydrogenases”. Biochem. J. 203: 707—715. PMID 6180732.
Literatura
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze
- Sarcosine+dehydrogenase на US National Library of Medicine Medical Subject Headings (MeSH)
- п
- р
- у
- EC1 Oksidoreduktaze /spisak
- EC2 Transferaze /spisak
- EC3 Hidrolaze /spisak
- EC4 Lijaze /spisak
- EC5 Izomeraze /spisak
- EC6 Ligaze /spisak
- B enzm: 1.1/2/3/4/5/6/7/8/10/11/13/14/15-18, 2.1/2/3/4/5/6/7/8, 2.7.10, 2.7.11-12, 3.1/2/3/4/5/6/7, 3.1.3.48, 3.4.21/22/23/24, 4.1/2/3/4/5/6, 5.1/2/3/4/99, 6.1-3/4/5-6
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