TXNRD1 |
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![](//upload.wikimedia.org/wikipedia/commons/thumb/3/38/Protein_TXNRD1_PDB_1h6v.png/250px-Protein_TXNRD1_PDB_1h6v.png) |
Available structures |
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PDB | Ortholog search: PDBe RCSB |
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List of PDB id codes |
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2CFY, 2J3N, 2ZZ0, 2ZZB, 2ZZC, 3QFA, 3QFB |
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Identifiers |
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Aliases | TXNRD1, GRIM-12, TR, TR1, TRXR1, TXNR, thioredoxin reductase 1 |
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External IDs | OMIM: 601112; MGI: 1354175; HomoloGene: 55733; GeneCards: TXNRD1; OMA:TXNRD1 - orthologs |
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Gene location (Human) |
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![Chromosome 12 (human)](//upload.wikimedia.org/wikipedia/commons/thumb/e/e7/Ideogram_human_chromosome_12.svg/300px-Ideogram_human_chromosome_12.svg.png) | Chr. | Chromosome 12 (human)[1] |
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| Band | 12q23.3 | Start | 104,215,779 bp[1] |
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End | 104,350,307 bp[1] |
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Gene location (Mouse) |
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![Chromosome 10 (mouse)](//upload.wikimedia.org/wikipedia/commons/thumb/4/4e/Ideogram_house_mouse_chromosome_10.svg/260px-Ideogram_house_mouse_chromosome_10.svg.png) | Chr. | Chromosome 10 (mouse)[2] |
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| Band | 10|10 C1 | Start | 82,669,785 bp[2] |
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End | 82,733,546 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - stromal cell of endometrium
- islet of Langerhans
- right adrenal gland
- right adrenal cortex
- left adrenal gland
- left adrenal cortex
- right coronary artery
- pericardium
- left coronary artery
- nasal epithelium
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| Top expressed in | - somite
- otic placode
- otic vesicle
- stroma of bone marrow
- primitive streak
- endothelial cell of lymphatic vessel
- ganglionic eminence
- saccule
- epiblast
- gastrula
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| More reference expression data |
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BioGPS | |
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Gene ontology |
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Molecular function | - protein-disulfide reductase activity
- methylselenol reductase activity
- flavin adenine dinucleotide binding
- methylseleninic acid reductase activity
- protein binding
- electron transfer activity
- oxidoreductase activity
- oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor
- thioredoxin-disulfide reductase activity
| Cellular component | - cytoplasm
- extracellular exosome
- nucleus
- fibrillar center
- nucleoplasm
- mitochondrion
- cytosol
| Biological process | - nucleobase-containing small molecule interconversion
- selenium compound metabolic process
- signal transduction
- cellular oxidant detoxification
- response to oxygen radical
- cell redox homeostasis
- regulation of lipid metabolic process
- cellular response to oxidative stress
- mesoderm formation
- gastrulation
- cell population proliferation
- electron transport chain
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | NM_182743 NM_001093771 NM_001261445 NM_001261446 NM_003330
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NM_182729 NM_182742 |
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NM_001042513 NM_001042514 NM_001042523 NM_015762 |
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RefSeq (protein) | NP_001087240 NP_001248374 NP_001248375 NP_003321 NP_877393
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NP_877419 NP_877420 |
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NP_001035978 NP_001035979 NP_001035988 NP_056577 |
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Location (UCSC) | Chr 12: 104.22 – 104.35 Mb | Chr 10: 82.67 – 82.73 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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