RBM28

Protein-coding gene in the species Homo sapiens
RBM28
Identifiers
AliasesRBM28, ANES, RNA binding motif protein 28
External IDsOMIM: 612074; MGI: 2655711; HomoloGene: 135952; GeneCards: RBM28; OMA:RBM28 - orthologs
Gene location (Human)
Chromosome 7 (human)
Chr.Chromosome 7 (human)[1]
Chromosome 7 (human)
Genomic location for RBM28
Genomic location for RBM28
Band7q32.1Start128,297,685 bp[1]
End128,343,908 bp[1]
Gene location (Mouse)
Chromosome 6 (mouse)
Chr.Chromosome 6 (mouse)[2]
Chromosome 6 (mouse)
Genomic location for RBM28
Genomic location for RBM28
Band6|6 A3.3Start29,123,575 bp[2]
End29,165,005 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • sural nerve

  • Achilles tendon

  • apex of heart

  • right auricle

  • gastrocnemius muscle

  • epithelium of colon

  • left ventricle

  • gastric mucosa

  • corpus callosum

  • subcutaneous adipose tissue
Top expressed in
  • tail of embryo

  • genital tubercle

  • epiblast

  • ventricular zone

  • somite

  • molar

  • right ventricle

  • morula

  • primary oocyte

  • zygote
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
  • nucleic acid binding
  • RNA binding
Cellular component
  • spliceosomal complex
  • nucleus
  • nucleolus
  • ribonucleoprotein complex
Biological process
  • mRNA processing
  • RNA splicing
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

55131

68272

Ensembl

ENSG00000106344

ENSMUSG00000029701

UniProt

Q9NW13

Q8CGC6

RefSeq (mRNA)

NM_001166135
NM_018077

NM_026650
NM_133925

RefSeq (protein)

NP_001159607
NP_060547

NP_598686

Location (UCSC)Chr 7: 128.3 – 128.34 MbChr 6: 29.12 – 29.17 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

RNA-binding protein 28 is a protein that in humans is encoded by the RBM28 gene.[5] It is a nucleolar component of the spliceosomal ribonucleoprotein complexes.[6]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000106344 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000029701 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: RBM28 RNA binding motif protein 28".
  6. ^ Damianov A, Kann M, Lane WS, Bindereif A (2006). "Human RBM28 protein is a specific nucleolar component of the spliceosomal snRNPs". Biol Chem. 387 (10–11): 1455–60. doi:10.1515/BC.2006.182. PMID 17081119. S2CID 12689948.

Further reading

  • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
  • Andersen JS, Lyon CE, Fox AH, et al. (2002). "Directed proteomic analysis of the human nucleolus". Curr. Biol. 12 (1): 1–11. Bibcode:2002CBio...12....1A. doi:10.1016/S0960-9822(01)00650-9. PMID 11790298. S2CID 14132033.
  • Scherl A, Couté Y, Déon C, et al. (2003). "Functional proteomic analysis of human nucleolus". Mol. Biol. Cell. 13 (11): 4100–9. doi:10.1091/mbc.E02-05-0271. PMC 133617. PMID 12429849.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Andersen JS, Lam YW, Leung AK, et al. (2005). "Nucleolar proteome dynamics". Nature. 433 (7021): 77–83. Bibcode:2005Natur.433...77A. doi:10.1038/nature03207. PMID 15635413. S2CID 4344740.
  • Damianov A, Kann M, Lane WS, Bindereif A (2006). "Human RBM28 protein is a specific nucleolar component of the spliceosomal snRNPs". Biol. Chem. 387 (10–11): 1455–60. doi:10.1515/BC.2006.182. PMID 17081119. S2CID 12689948.
  • v
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  • 1x4h: Solution structure of RRM domain in RNA-binding protein 28
    1x4h: Solution structure of RRM domain in RNA-binding protein 28


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