Osteomodulin

Protein-coding gene in the species Homo sapiens
OMD
Identifiers
AliasesOMD, OSAD, SLRR2C, osteomodulin, osteoadherin, osteoadherin proteoglycan
External IDsMGI: 1350918; HomoloGene: 3677; GeneCards: OMD; OMA:OMD - orthologs
Gene location (Human)
Chromosome 9 (human)
Chr.Chromosome 9 (human)[1]
Chromosome 9 (human)
Genomic location for OMD
Genomic location for OMD
Band9q22.31Start92,412,380 bp[1]
End92,424,471 bp[1]
Gene location (Mouse)
Chromosome 13 (mouse)
Chr.Chromosome 13 (mouse)[2]
Chromosome 13 (mouse)
Genomic location for OMD
Genomic location for OMD
Band13|13 A5Start49,735,938 bp[2]
End49,746,298 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • periodontal fiber

  • right coronary artery

  • thoracic aorta

  • ascending aorta

  • Descending thoracic aorta

  • tibia

  • Achilles tendon

  • left coronary artery

  • decidua

  • popliteal artery
Top expressed in
  • calvaria

  • intercostal muscle

  • molar

  • body of femur

  • skin of external ear

  • olfactory epithelium

  • trachea

  • ankle

  • fossa

  • lumbar spinal ganglion
More reference expression data
BioGPS


More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

4958

27047

Ensembl

ENSG00000127083

ENSMUSG00000048368

UniProt

Q99983

O35103

RefSeq (mRNA)

NM_005014

NM_012050
NM_001360708

RefSeq (protein)

NP_005005

NP_036180
NP_001347637

Location (UCSC)Chr 9: 92.41 – 92.42 MbChr 13: 49.74 – 49.75 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Osteomodulin (also called osteoadherin or osteoadherin proteoglycan) is a protein that in humans is encoded by the OMD gene.[5]


References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000127083 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000048368 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: OMD osteomodulin".

Further reading

  • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
  • Wendel M, Sommarin Y, Heinegård D (1998). "Bone matrix proteins: isolation and characterization of a novel cell-binding keratan sulfate proteoglycan (osteoadherin) from bovine bone". J. Cell Biol. 141 (3): 839–47. doi:10.1083/jcb.141.3.839. PMC 2132750. PMID 9566981.
  • Buchaille R, Couble ML, Magloire H, Bleicher F (2000). "Expression of the small leucine-rich proteoglycan osteoadherin/osteomodulin in human dental pulp and developing rat teeth". Bone. 27 (2): 265–70. doi:10.1016/S8756-3282(00)00310-0. PMID 10913920.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Lucchini M, Romeas A, Couble ML, et al. (2003). "TGF beta 1 signaling and stimulation of osteoadherin in human odontoblasts in vitro". Connect. Tissue Res. 43 (2–3): 345–53. doi:10.1080/713713482. PMID 12489179.
  • Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
  • Couble ML, Bleicher F, Farges JC, et al. (2004). "Immunodetection of osteoadherin in murine tooth extracellular matrices". Histochem. Cell Biol. 121 (1): 47–53. doi:10.1007/s00418-003-0608-2. PMID 14673660. S2CID 8160119.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.


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