Ceronapril
Chemical compound
- C09AA09 (WHO)
- 1-[(2S)-6-Amino-2-hydroxyhexanoyl]-L-proline, hydrogen (4-phenyl-butyl)phosphonate
- 111223-26-8
- 189729
- 164789
- X3MM60SOVP
- D03440
- DTXSID80891418
- Interactive image
- C1C[C@H](N(C1)C(=O)[C@H](CCCCN)OP(=O)(CCCCC2=CC=CC=C2)O)C(=O)O
InChI
- InChI=1S/C30H46NO7P/c1-4-28(33)37-30(22(2)3)38-39(36,18-12-11-15-23-13-7-5-8-14-23)21-27(32)31-20-25(19-26(31)29(34)35)24-16-9-6-10-17-24/h5,7-8,13-14,22,24-26,30H,4,6,9-12,15-21H2,1-3H3,(H,34,35)/t25-,26+,30?,39-/m1/s1 Y
- Key:BIDNLKIUORFRQP-YYTCENNOSA-N Y
Ceronapril (INN,[1] proposed trade names Ceranapril, Novopril) is a phosphonate ACE inhibitor[2] that was never marketed.[citation needed]
References
- ^ "International Nonproprietary Names for Pharmaceutical Substances (INN). Recommended International Nonproprietary Names (Rec. INN): List 31" (PDF). World Health Organization. p. 4. Retrieved 2 March 2017.
- ^ Tu JI, Brennan J, Stouffer B, Mantha S, Turabi N, Tsay HM (June 1992). "Radioimmunoassay for ceronapril, a new angiotensin-converting enzyme inhibitor, and its application to a pharmacokinetic study in healthy male volunteers". Therapeutic Drug Monitoring. 14 (3): 209–19. doi:10.1097/00007691-199206000-00007. PMID 1412607. S2CID 23854785.
- v
- t
- e
Antihypertensive drugs acting on the renin–angiotensin system (C09)
("-pril")
- Sulfhydryl-containing: Captopril
- Rentiapril
- Zofenopril
- Dicarboxylate-containing: Enalapril#
- Benazepril
- Cilazapril
- Delapril
- Imidapril
- Lisinopril (+amlodipine, +HCT)
- Moexipril
- Perindopril (+indapamide)
- Quinapril (+HCT)
- Ramipril
- Spirapril
- Temocapril
- Trandolapril
- Phosphonate-containing: Ceronapril
- Fosinopril (+HCT)
- Other/ungrouped: Alacepril
("-sartan")
("-kiren")
- Gemopatrilat
- Ilepatril
- Omapatrilat
- Sampatrilat
- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
This drug article relating to the cardiovascular system is a stub. You can help Wikipedia by expanding it. |
- v
- t
- e
This stereochemistry article is a stub. You can help Wikipedia by expanding it. |
- v
- t
- e